Fissure sealant application is an efficient method for dental caries prevention. Self-etch fissure sealants (SE-FS) eliminate the separate etching step for bonding. The present study investigated the micro-shear bond strength (μSBS) of a SE-FS (Prevent seal®, Itena©, Paris, France) to enamel pretreated with different methods including Er,Cr:YSGG laser, under noncontaminated and saliva-contaminated conditions. Sixty human premolars were sectioned into halves and randomly assigned into two groups of saliva-contaminated and noncontaminated.
